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Chapters

IgG receptors and their role in antibody trafficking

Download thesis from university repository (when available)

Chapter 1

General introduction and scope of the thesis

Chapter 2

Glycine 236 in the Lower Hinge Region of Human lgGl Differentiates FcyR from Complement Effector Function abstract

Chapter 3

Reduced FcRn-mediated transcytosis of lgG2 due to a missing Glycine in its lower hinge abstract

Chapter 4

The Fab region of lgG impairs the internalization pathway of FcRn upon Fc engagement abstract

Chapter 5

Fab glycans hinder FcRn-mediated placental transport abstract

Chapter 6

Human lgE does not bind to human FcRn abstract

Chapter 7

Human FcyRs mediate lgG internalization and delivery to FcRn

Chapter 8

General discussion

Chapter 9

Natural and engineered structural modifications of lgG antibodies