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Chapters

Not all that glitters is gold – platelet transfusions for preterm neonates

Download thesis (university repository)

Chapter 1

General introduction and outline of the thesis

PART I. WHAT DO WE KNOW ABOUT THROMBOCYTOPENIA, TRANSFUSIONS AND BLEEDING IN NEONATES?

Chapter 2 

Neonatal thrombocytopenia: etiology, management and outcome. 
Expert Review of Hematology 2014;7(3):387-95.

Chapter 3 

Are thrombocytopenia and platelet transfusions associated with major bleeding in preterm neonates? A systematic review. 
Blood Reviews 2019;36:1-9

Chapter 4 

Early-Onset Thrombocytopenia in Small-For-Gestational-Age Neonates: A Retrospective Cohort Study. 
PLoS One 2016 May 13;11(5):e 0154853.

PART II. DO PLATELET TRANSFUSIONS WORK?

Chapter 5

A randomized trial of neonatal platelet transfusion thresholds.
New England Journal of Medicine 2019;380(3):242-251.

Chapter 6 

Preterm neonates benefit from low prophylactic platelet transfusion threshold despite varying risk of bleeding or death. 
Revised version published in: Blood 2019 Oct 24. Epub ahead of print.

Chapter 7 

Do platelet transfusions reduce bleeding risk in preterm neonates with severe thrombocytopenia? A time-dependent propensity score matched cohort analysis.

PART III. CAN WE PREDICT MAJOR BLEEDING IN NEONATES?

Chapter 8

 
Dynamic prediction of bleeding risk in thrombocytopenic preterm neonates.
Haematologica 2019 Nov;104(11):2300-2306

PART IV. DISCUSSION AND FUTURE PERSPECTIVES

Chapter 9

Platelet and red cell transfusions for neonates: lifesavers or trojan horses? 
Revised version published in: Exp Rev Haem 2019 Oct; 12(10):797-800.