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Chapters

Switching Gear: Hemoglobin switching throughout erythropoiesis

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Chapter 1

General Introduction

Chapter 2

Large-scale in-vitro production of red blood cells from human peripheral blood mononuclear cells abstract

Chapter 3

CD14+ monocytes repress gamma globin expression at early stages of erythropoiesis

Chapter 4

Epigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts

Chapter 5

Hemoglobin switching in mice carrying the Klf1Nan variant abstract

Chapter 6

General Discussion