To settle or wander: Transcriptional regulation and recall responses of tissue-resident memory T cells

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Chapter 1

General Introduction 

Chapter 2

Hobit and Blimp1 instruct a universal transcriptional program of tissue-residency in lymphocytes Abstract

Chapter 3

Blimp-1 rather than Ho bit drives the formation of tissue­resident memory CD8+ T cells in the lungs Abstract

Chapter 4

Blimp-1 induces and Hobit maintains the cytotoxic mediator granzyme B in CD8 T cells Abstract

Chapter 5

Eomes regulates early establishment of the Hobit+ TRM lineage

Chapter 6

Hobit identifies tissue-resident memory CD4+ T cell development after viral and bacterial infection 

Chapter 7

Trm maintenance is regulated by tissue damage via P2RX7 Abstract

Chapter 8

Tissue-resident memory CD8+ T cells shape local and systemic secondary T cell responses Abstract

Chapter 9

Limited contribution of circulating memory CD8+ T cells to resident memory at mucosal sites after reinfection 

Chapter 10

General Discussion