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Chapters

Filling the gaps; The endothelium in regulating vascular leakage and leukocyte extravasation

Thesis at university repositirory

 

Chapter 1

General introduction

Chapter 2

Leukocyte transendothelial migration: A local affair abstract

Chapter 3

F-actin rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signaling abstract

Chapter 4

Endothelial RhoB and RhoC are dispensable for leukocyte diapedesis and for maintaining vascular integrity during diapedesis abstract

Chapter 5

The Rho-GEFs FGD5 and Tuba differentially regulate the small GTPase Cdc42 to control leukocyte extravasation and vascular permeability

Chapter 6

Stiffness-induced endothelial DLC-1 expression forces leukocyte spreading through stabilization of the ICAM-1 adhesome

Chapter 7

Rac1 activation by the endothelial GEF Tiam1 marks sites for leukocyte diapedesis through guiding junctional membrane ruffles

Chapter 8

Summary and concluding remarks