Chapters
Tuning the Show: Genetic engineering to unravel antigen presentation by the Human Leukocyte Antigen class IDownload thesis (university repository, when available)
Chapter 1
General introduction and scope of this thesis
Chapter 2
PAKC: A novel panel of HLA class I antigen presentation machinery knockout cells from the same genetic origin Abstract
Chapter 3
Healthy cells functionally present TAP-independent SSR1 peptides: implications for selection of clinically relevant antigens Abstract
Chapter 4
HLA-I allelic dependencies on components of the peptide-loading complex
Chapter 5
The role of glycosphingolipids in immune cell functions Abstract
Chapter 6
The SPPL3-defined glycosphingolipid repertoire orchestrates HLA class I-mediated immune responses Abstract
Chapter 7
Summarizing discussion
