Chapters
A suit of armor around ADAMTS13; Exploring paths towards resistance against autoantibodies of immune TTP patientsDownload thesis (when available from university repository)
Chapter 1
The “Nautical Chart” of Thrombotic Thrombocytopenic Purpura – a General Introduction
Chapter 2
Dissecting the pathophysiology of immune thrombotic thrombocytopenic purpura: interplay between genes and environmental triggers Abstract
Chapter 3
Immunogenic hotspots in the spacer domain of ADAMTS13 in immune-mediated thrombotic thrombocytopenic purpura Abstract
Chapter 4
Modifying ADAMTS13 to modulate binding of pathogenic autoantibodies of patients with acquired thrombotic thrombocytopenic purpura Abstract
Chapter 5
N-glycan mediated shielding of ADAMTS13 prevents binding of pathogenic autoantibodies in immune-mediated TTP Abstract
Chapter 6
Modelling-assisted identification of CUB1/2 domain residues involved in maintaining ADAMTS13 in a closed conformation
Chapter 7
General Discussion
