On the variation of SMIM1 expression |noVel insights in erythrocytes and during erythropoiesis

Download thesis from university repository 

Chapter 1 

General Introduction and scope of thesis

Chapter 2 

Development of a recombinant anti-Vel immunoglobulin M to identify Vel-negative donors Abstract

Chapter 3

Identification of a novel single-nucleotide mutation in SMIM1 gene that results in low Vel antigen expression Abstract

Chapter 4

SMIM1 missense mutations exert their effect on wild type Vel expression late in erythroid differentiation Abstract

Chapter 5

SMIM1 serine phosphorylation regulates SMIM1 protein levels during erythroid differentiation

Chapter 6

General Discussion