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Chapters

Weibel-Palade body logistics: express delivery in the vasculature

Chapter 1

General introduction

Chapter 2

Exocytosis of Weibel-Palade bodies: how to unpack a vascular emergency kit Abstract

Chapter 3

Weibel-Palade body localized syntaxin-3 modulates von Willebrand factor secretion from endothelial cells Abstract

Chapter 4

Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowwth endothelial cells Abstract

Chapter 5

Interaction networks of Weibel-Palade body regulators syntaxin-3 and syntaxin binding protein 5 in endothelial cells Abstract

Chapter 6

A CRISPR/Cas9 engineered Von Willebrand factor deficient endothelial cell model shows alternative trafficking of Weibel-Palade body proteins

Chapter 7

General discussion