University repository

Chapter 1

Introduction
How neutrophils kill fungi
Immunological Reviews 2016 (273) Sept; in press

Chapter 2

Invasive fungal infection and impaired neutrophil killing in human CARD9 deficiency’’
Blood 2013; 121(13):2385-92.

Chapter 3

Chronic Candida albicans meningitis in a 4-year-old girl with a homozygous mutation in the CARD9 gene (Q295X)
Pediatr Infect Dis J 2015; 34(9):999-1002.

Chapter 4

Extrapulmonary Aspergillus infection in patients with CARD9 Deficiency.
J Allergy Clin Immunol 2016; resubmitted

Chapter 5

Defects in neutrophil granule mobilization and bactericidal activity in familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) syndrome caused by STXBP2/Munc18-2 mutations.
Blood 2013; 122(1):109-11.

Chapter 6

Impaired microbial killing by neutrophils from patients with PKC delta deficiency.
J Allergy Clin Immunol 2015; 136(5):1404-7.
http://www.ncbi.nlm.nih.gov/pubmed/26233929

Chapter 7

Neutrophil specific granule deficiency and impaired NETosis in Gray Platelet Syndrome.
J Clin Invest 2016; submitted

Chapter 8

Pro-inflammatory response to fungal but not to bacterial pathogens in Chronic Granulomatous Disease.
J Allergy Clin Immunol 2016 May; in press

Chapter 9

Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects.
Blood 2014; 124(4):590-7.

Chapter 10

Human neutrophils employ distinct mechanisms for the killing of Aspergillus fumigatus conidia and hyphae: evidence from phagocyte defects.
J Immunol 2016; 196(3):1272-83.

Chapter 11

G-CSF/dexamethasone mobilized granulocytes for transfusion purposes are impaired in Candida albicans killing.
Haematologica 2016; 101(5):587-96.

Chapter 12

Characterization of buffy-coat-derived granulocytes for clinical use: a comparison with GCSF/dexamethasone-treated donor-derived products.
Vox Sang 2016; submitted

Chapter 13

Discussion