Chapter 1

General introduction

Chapter 2

Dectin-1 deficiency does not affect atherosclerosis development in mice.
Atherosclerosis 2015; 239(2):318-21.

Chapter 3

PKCδ is dispensible for oxLDL uptake and foam cell formation by human and murine macrophages.
Cardiovasc Res 2014; 104(3):467-76.

Chapter 4

Impaired microbial killing by neutrophils from patients with PKCδ deficiency.
J Allergy Clin Immunol 2015; 136(5):1404-1407.e10.

Chapter 5

The inhibitory receptor Signal Regulatory Protein alpha (SIRPα) is expressed by mouse B1 cells and is associated with atherosclerosis development by limiting natural antibody production.

Chapter 6

Summary, Conclusions and Future Perspectives

Chapter 7

Nederlandse Samenvatting