Henk (H.) Schonewille PhD


Medical chemical technician, Transfusion Medicine


‘Red blood cell alloimmunization after blood transfusion’
Promotor: Prof A Brand
16 January 2008 - University of Leiden

Research interests

Red blood cell (RBC) alloimmunization is a frequent complication of blood transfusions and can hamper optimal transfusion support. The aim of the research-line is to identify relevant factors which may help to predict which recipients will become (multi-)immunized after RBC transfusion and for whom extended matching between donor and patient is cost-effective. Our studies focus on the epidemiology of alloimmunization, the relation with antigens on other blood cells and genetic factors involved in the immune response.


  • Clinical studies
  • Serology
  • PCR


2014-present Post-doc fellow Dept of Experimental Immunohematology, Sanquin Research
2008-2014 PhD Medicine (University of Leiden)
2008 Researcher at the Dept of Transfusion Medicine, Sanquin Research, Leiden

Other publications

Schonewille H, van Zijl AM, Wijermans PW. The importance of antibodies against low incidence red blood cell antigens in complete and abbreviated crossmatching. Transfusion 2003; 43:939-44.

Schonewille H, Haak HL, van Zijl AM. RBC antibody persistence. Transfusion 2000; 40:1127-31.

Schonewille H, Haak HL, van Zijl AM. Alloimmunization after blood transfusion in patients with hematologic and oncologic diseases. Transfusion 1999; 39:763-71.

Schonewille H, Haak HL, Kerkhofs H, Gerrits WBJ. The effect of anticoagulants on the size of platelets in blood smears in the course of time. Clin Lab Haemat. 1991; 13:67-74.

Haak HL, Kerkhofs H, van de Linden JSM, Schonewille H, Gonggrijp van der Sanden-van der Meer HS, Hermans J. Significance of in vitro cultures in myelodysplastic syndromes. Scand J Haematol 1986;.37:380-9.