Carlijn (C.) Voermans PhD


Cell biology, hematopoiesis and transplantation biology


Migration of human hematopoietic progenitor cells
Promotor: Prof D. Roos, PhD and Prof A.E.G.Kr von dem Borne, MD PhD
co-promotors: Prof C.E. van der Schoot, MD, PhD en Dr. W.R. Gerritsen, MD PhD
Maart 2001

Research interests

Projects are focused on bone marrow micro-environment; i.e. hematopoietic stem cell regeneration, megakaryocytopoiesis, mesenchymal stromal cell (MSC) migration and the development of new cellular therapies


  • Selection and culturing of CD34+ cells
  • In vitro adhesion/migration assays
  • Lentiviral transduction of CD34+ cells
  • Micro-array
  • Flowcytometry
  • rt-PCR
  • Isolation and culturing of MSC
  • In vivo analysis of stem cell homing


2006-present Senior scientist/head of Laboratory for Stem Cell transplantation of Sanquin Research, Amsterdam
2004-2005 Postdoctoral fellow at Duke University Medical Center, dept Pharmacology and Cancer Biology, Durham (NC), USA at the laboratory of Dr. T. Reya
2001-2004 Postdoctoral fellow/head of laboratory for Stem Cell transplantation of Sanquin Research Amsterdam
1996-2000 PhD student at Dept of Experimental Immunohematology, CLB/ SanquinAmsterdam and the Netherlands Cancer Institute, Dept of Medical Oncology Amsterdam, the Netherlands. Research project: Migration of human hematopoietic progenitor cells
1995-1996 Research fellow at the Nelson Institute of environmental Medicine, New York University Medical Centre Tuxedo (NY), USA
1989-1995 University of Amsterdam, Medical Biology

Other publications

Congdon KL, Voermans C, Ferguson EC, DiMascio LN, Uqoezwa M, Zhao C, Reya T. Activation of Wnt signaling in hematopoietic regeneration. Stem Cells 2008; 26(5):1202-10. Epub 2008 Feb 28

DiMascio L, Voermans C, Uqoezwa M, Duncan A, Lu D, Wu J, Sankar U, Reya T. Identification of adiponectin as a novel hemopoietic stem cell growth factor. J Immunol 2007; 178(6):3511-20

Rattis FM, Voermans C, Reya T. Wnt signaling in the stem cell niche. Curr Opin Hematol 2004; 11(2):88-94. Review. Erratum in: Curr Opin Hematol. 2004;11(4):284