University repository

Chapter 1

General introduction and scope of the thesis

Chapter 2

Nucleosomes and neutrophil activation in sickle cell disease painful crisis
Haematologica. 2013 Nov;98(11):1797-803

Chapter 3

Inflammatory and endothelial markers during vaso-occlusive crisis in sickle cell disease

Chapter 4

Dynamics of von Willebrand factor reactivity in sickle cell disease during vaso-occlusive crisis and steady state
J Thromb Haemost. 2017 Apr 29

Chapter 5

Free iron in sera of patients with sickle cell disease mediates the release of neutrophil extracellular traps

Chapter 6

Urinary zinc loss in sickle cell disease primarily due to increased bone degradation
Am J Hematol. 2016 Jun;91(6):E311-2

Chapter 7

N-terminal pro-B-type natriuretic peptide, tricuspid jet flow velocity and death in adults with sickle cell disease
Am J Hematol. 2015 Apr;90(4):E75-6

Chapter 8

Prospective evaluation of chronic organ damage in adult sickle cell patients. A seven-year follow-up study

Chapter 9

Summary of results and future perspectives