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General research on TNF inhibitors

  • Therapeutic TNF Inhibitors can Differentially Stabilize Trimeric TNF by Inhibiting Monomer Exchange. van Schie et al., Sci Rep. 2016 Sep 8;6:32747.

 

  • Comparison of Three Assays to Quantify Infliximab, Adalimumab, and Etanercept Serum Concentrations. van Bezooijen et al., Ther Drug Monit. 2016 Aug;38(4):432-8. doi: 10.1097/FTD.0000000000000310. PMID: 27120178.

 

  • The antibody response against human and chimeric anti-TNF therapeutic antibodies primarily targets the TNF binding region. van Schie et al.,  Ann Rheum Dis 2015; 74(1):311-4

 

  • Cross-reactive and pre-existing antibodies to therapeutic antibodies--Effects on treatment and immunogenicity. van Schie et al., MAbs. 2015;7(4):662-71.