PhD student: Platelet (phospho)proteomes in health and disease

Medical Priority Bleeding and Hemostasis

The medical priority Bleeding and Hemostasis is an international frontrunner in applying state-of-the-art mass spectrometry-based proteomics in the area of benign hematology. We are a vibrant, international group of 35-40 colleagues (consisting of group leaders, postdocs, PhD students and technicians) that study the various aspects of hemostatic networks. Our department has academic affiliations with high-ranking universities in the Netherlands, such as Utrecht University and the University of Amsterdam. The department’s research program benefits from excellent research facilities, which include the latest technology for biomolecular mass spectrometry, imaging and cell sorting. Platelet (phospho)proteomes in health and disease

We are looking for a PhD student to join the mission of the Medical Priority Bleeding & Hemostasis of Sanquin Research to improve diagnosis and treatment of patients suffering from acquired and congenital bleeding disorders.

Platelets are essential for primary hemostasis and dysfunctionality is associated with hemostatic disorders, including bleeding and thrombosis. In this PhD project, we aim to advance our molecular understanding of platelet biology through integrated complementary mass spectrometry-based approaches, including (phospho)proteomics, peptidomics and metabolomics. In addition, we will relate platelet signaling mechanisms to genetic background and (rare) disease. We especially encourage applications of talented researchers with the skills and ambition to integrate ‘omics’-based profiling data with the ultimate goal to identify and study novel pathogenic mechanisms underlying platelet (dys)function.

Requirements

- A MSc degree in (systems) biology and/or (bio)molecular/biomedical/pharmaceutical/bio-analytical sciences or equivalent. Pro-active and eager to learn and employ a variety of proteomics and bio-informatics approaches to address platelet biology;
- Good communication skills in English;
- The ability to work efficiently independently, but also in close collaboration with a multidisciplinary and international team composed of highly ambitious young researchers.

Conditions of employment

We offer unique research opportunities in a dynamic environment. Nowhere else in the world you will find an organization that combines medical, pharmaceutical, diagnostic and scientific research under one roof.  In addition to a challenging project in a multi-disciplinary and enthusiastic team we offer:

- Salary and working conditions conform CAO Sanquin;
- Temporary position for the duration of 4 years (PhD student)
- A full time contract of 36 hours per week;
- 8,33% end-of-year bonus;
- 8,33% holiday allowance;
- Partial reimbursement of travel expenses;
- Pension plan with Pensioenfonds Zorg & Welzijn (PFZW), Sanquin contributes 65%;
- Collective discounts on various insurances;
- At fulltime employment (36 hours) 201 hours of leave per annum.

Learn more about our terms of employment at https://www.sanquin.org/working-at/who-we-are/employment-conditions.

Further information

For further information, please contact Maartje van den Biggelaar [email protected]. Does this vacancy trigger you and do you recognize yourself in this profile? We would like to receive your application, accompanied by curriculum vitae and cover letter, including a detailed motivation, before September 1st 2025. Please apply using the button below!

Please note that we will only process applications from candidates who are eligible to apply for a work permit for the EU. A pre-employment screening will be part of the onboarding procedure.

Acquisition is not appreciated. Sanquin does not accept unsolicited help from agencies for vacancies. CV's sent (in any form whatsoever) by placement agencies to any Sanquin employee without a valid written assignment by HR Sanquin will be considered property of Sanquin for which no compensation is owed in any way..