Willem (W. J. J.) Falkenburg MD
Medicine, Utrecht University
My project focuses on improving the characterization of the rheumatoid factor response and other antibody-against-antibody responses in Rheumatoid Arthritis (RA). This will hopefully lead to better prediction of onset and course of the disease and add to our understanding of the role of antibody responses in the pathogenesis of RA.
|2013-present||PhD student at Reade, Eular center of excellence in rheumatology and the Dept of Immunopathology, Sanquin Research|
|2013||Medical Resident, Tergooi Hospitals, Hilversum, division of Internal Medicine|
|2011-2012||Medical Resident, Haga Teaching Hospital, The Hague, division of Hematology|
|2011||Research Traineeship, Dept of Rheumatology and Clinical Immunology, University Medical Center, Utrecht|
|2010-2011||Sub-internship Cardiology, St. Antonius Hospital, Nieuwegein|
|2008-2009||Visiting Research Fellow, National Heart, Lung and Blood Institute (NHLBI), Bethesda, Maryland, USA|
|2008||Research Traineeship, Laboratory of Experimental Hematology, Leiden University Medical Center, Leiden|
Nieuwenhuizen L, Falkenburg WJ, Schutgens RE, Roosendaal G, van Veghel K, Biesma DH, Lafeber FP. Stimulation of naïve monocytes and PBMCs with coagulation proteases results in thrombin-mediated and PAR-1-dependent cytokine release and cell proliferation in PBMCs only. Scand J Immunol 2013; 77(5):339-49.
Falkenburg WJ, Melenhorst JJ, van de Meent M, Kester MG, Hombrink P, Heemskerk MH, Hagedoorn RS, Gostick E, Price DA, Falkenburg JH, Barrett AJ, Jedema I. Allogeneic HLA-A2-restricted WT1-specific T cells from mismatched donors are highly reactive but show off-target promiscuity. J Immunol 2011; 187(5):2824-33.