Sanquin Research is recruiting two new group leadersJoghem van Loghem Career Fellowships (tenure track)
We are looking for one early and one mid-career tenure track group leader. These new colleagues are expected to contribute to the aims of one or more of our four strategic research themes.
About Sanquin Research & Lab services
Sanquin Blood Supply Foundation uniquely combines medical, diagnostic, blood bank and research activities. With 2,000 committed colleagues and 345,000 blood donors, we aim to provide a better life for 300,000 patients each year.
The Division of Research & Lab Services of Sanquin is home to 250 researchers and technicians, including over 60 PhD students. Thirteen senior staff hold professorships at one of the Dutch universities. Research at Sanquin is organized in four strategic themes: Anemia, Bleeding & Hemostasis, Immunity & Inflammation, and Immune Therapy. The joint mission of research at Sanquin is to invent novel methods and approaches using blood cells and blood products to prevent, diagnose, treat, or cure disease in donors and patients. Research activities cover the full spectrum of early inventions, development into novel products and services, donor studies, and clinical studies in patients.
Our research labs are equipped with state-of-the-art facilities, including flow cytometry and cell sorting, macromolecular mass spectrometry and proteomics, and imaging. Many of our scientists have academic affiliations with Dutch Universities and University Medical Centers. Sanquin is strategically located in Amsterdam, with a special tie to the AmsterdamUMC (Joint Landsteiner Laboratory).
Professor Joghem van Loghem was the first scientific director (1950-1978) of CLB, the Central Laboratory for the Blood Transfusion Service of the Netherlands Red Cross, one of Sanquin’s predecessors. He was renowned for his work in blood group serology and immunohematology. The Foundation Joghem van Loghem is funding these two career fellowships.
Our research focus
The focus of our four strategic research themes are:
We aim to increase the efficiency of blood transfusion by improving donor health and behavior, suitability of transfusion products for specific patient groups, and clinical outcome of transfused erythrocytes. We investigate the production of cultured blood for various therapeutic purposes, for which we need to develop cost-effective production of erythrocytes in bioreactors. In addition, we aim to reduce the need of transfusion for chronically anemic patients and its adverse events, by finding alternative treatments. Read more
Bleeding and Hemostasis
We aim to improve diagnosis and treatment of patients with congenital and/or acquired hemostatic disorders. We will extend our research on the biology of megakaryocytes, blood platelets and blood coagulation factors with the overall aim of further improving omics-guided approaches for restoring hemostasis in patients suffering from bleeding symptoms. Read more
Immunity and Inflammation
We investigate immune responses to develop novel diagnostics, targeted therapies and personalized medicine, to prevent unwanted side effects from transfusion of blood cells or products. This includes structural and functional characterization of the antibodies, complement and immune cells involved in these responses, causing tissue damage, organ dysfunction and/or blood cell destruction. Read more
Immune cell therapies have proven effective to fight infections and cancer. We study immune cell differentiation, function and control, with a focus on T cells, B cells, innate lymphoid cells and neutrophils. We seek to obtain fundamental understanding of immune cell differentiation to develop innovative cellular products, that are clinically implemented in the Sanquin Laboratory of Cell Therapy and by strong ties with (academic) hospitals. Read more
We anticipate the two newly recruited scientists to contribute with their unique expertise, complementing our existing research portfolio. This includes inflammation and complement research, genetic and cellular approaches to correct and cure hematological disorders, as well as translational bioinformaticians with proven expertise to successfully integrate clinical and large “omics” based profiling data-sets in the area of transfusion medicine.
We offer an international - academically oriented - research environment with state of-the-art equipment. You will have the opportunity to apply for internal and external funding to expand your group and if successful to apply for a permanent position as group leader.
|Early career fellowship||Mid career fellowship|
|Duration 3 years||Duration 4 years|
|Own salary||Own salary|
|Bench fee||Bench fee|
|Part-time technician||Part-time technician|
|PhD student (4 years)|
If you are interested in one of these two positions, please apply here by submitting your extended CV, before the 5th of August together with an outline of the contribution you expect to be able to make towards our research programme (max 2 pages).
After a pre-selection we will ask a number of suitable candidates to present their ideas for a more detailed research proposal in person, after which a final selection will be made.
More information may be obtained from the Director of Research by filling out the contact form below.