Factor H family proteins in health and infectious disease

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Chapter 1

General introduction and scope of this thesis.

Chapter 2

Factor H-related (FHR)-1 and FHR-2 form homo- and heterodimers, while FHR-5 circulates only as homodimer in human plasma. Abstract

Chapter 3

Reference intervals of factor H and factor H-related proteins in healthy children. Abstract

Chapter 4

Complement factor H (FH) and the FH-related proteins during pediatric meningococcal disease.

Chapter 5

Complement factor H levels associate with Plasmodium falciparum malaria susceptibility and severity. Abstract

Chapter 6

Summarizing discussion.