Steven (S.W.) de Taeye PhD

Immunoglobulin Research, Structure & function of antibodies LinkedIn

Training

Molecular Biology / Virology

Research interests

Structure and function of antibodies, humoral immunity, IgG polymorphisms

Technology

  • Mammalian cell culture
  • Transfection and cloning
  • SPR
  • FACS
  • Myeloid cell binding/activation assays
  • Complement activation assays

Resume

2016-present Postdoctoral fellow at Dept of Experimental Immunohematology and Dept of Immunopathology, Sanquin Research, Amsterdam
2012-2016 PhD program in Virology at Department of Experimental Virology, University of Amsterdam, AMC, Amsterdam
2006-2012 MSc in Biomedical Sciences at University of Amsterdam, Amsterdam

Other publications

  • de Taeye SW, Ozorowski G, Torrents de la Peña A, Guttman M, Julien JP, van den Kerkhof TL, Burger JA, Pritchard LK, Pugach P, Yasmeen A, Crampton J, Hu J, Bontjer I, Torres JL, Arendt H, DeStefano J, Koff WC, Schuitemaker H, Eggink D, Berkhout B, Dean H, LaBranche C, Crotty S, Crispin M, Montefiori DC, Klasse PJ, Lee KK, Moore JP, Wilson IA, Ward AB, Sanders RW. Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes.  2015 Dec 17;163(7):1702-15.
  • de Taeye SW, Moore JP, Sanders RW. HIV-1 Envelope Trimer Design and Immunization Strategies To Induce Broadly Neutralizing Antibodies.  2016 Mar;37(3):221-232.
  • de Taeye SW, de la Peña AT, Vecchione A, Scutigliani E, Sliepen K, Burger JA, van der Woude P, Schorcht A, Schermer EE, van Gils MJ, LaBranche CC, Montefiori DC, Wilson IA, Moore JP, Ward AB, Sanders RW. Stabilization of the gp120 V3 loop through hydrophobic interactions reduces the immunodominant V3-directed non-neutralizing response to HIV-1 envelope trimers. J Biol Chem. 2018 Feb 2;293(5):1688-1701.
  • Torrents de la Peña A*1 de Taeye SW*1, Sliepen K, LaBranche CC, Burger JA, Schermer EE, Montefiori DC, Moore JP, Klasse PJ, Sanders RW. Immunogenicity in Rabbits of HIV-1 SOSIP Trimers from Clades A, B, and C, Given Individually, Sequentially, or in Combination.  2018 Mar 28;92(8). pii: e01957-17
  • de Taeye SW, Go EP, Sliepen K, Torrents de la Peña A, Badal K, Medina-Ramirez M, Lee WH, Desaire H, Wilson IA, Moore JP, Ward AB, Sanders RW. HXT5 expression is under control of STRE and HAP elements in the HXT5 promoter.  2019 Feb 6 pii: jbc.RA118.005396.