Christina (C) Grosserichter-Wagener



Research interests

  • Humoral Immunity
  • Function and structure Immunoglobulins
  • Generation rabbit monoclonal antibodies


  • FACS
  • Mammalian cell culture
  • Transfection and cloning



2018 - present

Postdoctoral fellow at Department of Immunopathology, Sanquin Research, Amsterdam

2012- 2018

PhD program at Department of Immunology, Erasmus MC University Medical Center, Rotterdam

2010 - 2012

MSC in Infection and Immunity, Erasmus University, Rotterdam

Other publications

Looman KIM, van Meel ER, Grosserichter-Wagener C, Vissers FJM, Klingenberg JH, de Jong NW, et al. Associations of Th2, Th17, Treg cells, and IgA(+) memory B cells with atopic disease in children: The Generation R Study.  Allergy 2020;75(1):178-87

Grosserichter-Wagener C, Radjabzadeh D, van der Weide H, Smit KN, Kraaij R, Hays JP, et al. Differences in Systemic IgA Reactivity and Circulating Th Subsets in Healthy Volunteers With Specific Microbiota Enterotypes.  Front Immunol. 2019;10:341

Laksono BM, Grosserichter-Wagener C, de Vries RD, Langeveld SAG, Brem MD, van Dongen JJM, et al. In Vitro Measles Virus Infection of Human Lymphocyte Subsets Demonstrates High Susceptibility and Permissiveness of both Naive and Memory B Cells. J Virol.2018;92(8)

Mitsuiki N, Yang X, Bartol SJ, Grosserichter-Wagener C, Kosaka Y, Takada H, et al. Mutations in Bruton's tyrosine kinase impair IgA responses. Int J Hematol.2015;101(3):305-13

Berkowska MA, Schickel JN, Grosserichter-Wagener C, de Ridder D, Ng YS, van Dongen JJ, et al. Circulating Human CD27-IgA+ Memory B Cells Recognize Bacteria with Polyreactive Igs.J Immunol.2015;195(4):1417-26

Berkowska MA, Grosserichter-Wagener C, Adriaansen HJ, de Ridder D, Mirani-Oostdijk KP, Agteresch HJ, et al. Persistent polyclonal B-cell lymphocytosis: extensively proliferated CD27+IgM+IgD+ memory B cells with a distinctive immunophenotype. Leukemia.2014;28(7):1560-4

Perez-Andres M, Grosserichter-Wagener C, Teodosio C, van Dongen JJ, Orfao A, van Zelm MC. The nature of circulating CD27+CD43+ B cells. J Exp Med.2011;208(13):2565-6

Berkowska MA, Driessen GJ, Bikos V, Grosserichter-Wagener C, Stamatopoulos K, Cerutti A, et al. Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathwaysBlood 2011;118(8):2150-8