Erythropoiesis in Healthy and Deregulated Hematopoiesis



Publications Micha Nethe (before 2018) 


Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma.  Kas SM, de Ruiter JR, Schipper K, Annunziato S, Schut E, Klarenbeek S, Drenth AP, van der Burg E, Klijn C, Ten Hoeve JJ, Adams DJ, Koudijs MJ, Wesseling J, Nethe M, Wessels LFA, Jonkers J. Nat Genet. 2017 Aug;49(8):1219-1230. doi: 10.1038/ng.3905. Epub 2017 Jun 26

PTEN Loss in E-Cadherin-Deficient Mouse Mammary Epithelial Cells Rescues Apoptosis and Results in Development of Classical Invasive Lobular Carcinoma. Boelens MC, Nethe M, Klarenbeek S, de Ruiter JR, Schut E, Bonzanni N, Zeeman AL, Wientjens E, van der Burg E, Wessels L, van Amerongen R, Jonkers J. Cell Rep. 2016 Aug 23;16(8):2087-2101. doi: 10.1016/j.celrep.2016.07.059. Epub 2016 Aug 11.

Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland. Annunziato S, Kas SM, Nethe M, Yücel H, Del Bravo J, Pritchard C, Bin Ali R, van Gerwen B, Siteur B, Drenth AP, Schut E, van de Ven M, Boelens MC, Klarenbeek S, Huijbers IJ, van Miltenburg MH, Jonkers J. Genes Dev. 2016 Jun 15;30(12):1470-80. doi: 10.1101/gad.279190.116.

Rac1 acts in conjunction with Nedd4 and dishevelled-1 to promote maturation of cell-cell contacts. Nethe M, de Kreuk BJ, Tauriello DV, Anthony EC, Snoek B, Stumpel T, Salinas PC, Maurice MM, Geerts D, Deelder AM, Hensbergen PJ, Hordijk PL. J Cell Sci. 2012 Jul 15;125(Pt 14):3430-42. doi: 10.1242/jcs.100925. Epub 2012 Mar 30.

Ubiquitin links to cytoskeletal dynamics, cell adhesion and migration. Schaefer A, Nethe M, Hordijk PL. Biochem J. 2012 Feb 15;442(1):13-25. doi: 10.1042/BJ20111815. Review.

Altered intracellular localization and mobility of SBDS protein upon mutation in Shwachman-Diamond syndrome. Orelio C, van der Sluis RM, Verkuijlen P, Nethe M, Hordijk PL, van den Berg TK, Kuijpers TW. PLoS One. 2011;6(6):e20727. doi: 10.1371/journal.pone.0020727. Epub 2011 Jun 13.

The F-BAR domain protein PACSIN2 associates with Rac1 and regulates cell spreading and migration. de Kreuk BJ, Nethe M, Fernandez-Borja M, Anthony EC, Hensbergen PJ, Deelder AM, Plomann M, Hordijk PL. J Cell Sci. 2011 Jul 15;124(Pt 14):2375-88. doi: 10.1242/jcs.080630. Epub 2011 Jun 21.

The role of ubiquitylation and degradation in RhoGTPase signalling. Nethe M, Hordijk PL. J Cell Sci. 2010 Dec 1;123(Pt 23):4011-8. doi: 10.1242/jcs.078360. Review.

A model for phospho-caveolin-1-driven turnover of focal adhesions. Nethe M, Hordijk PL. Cell Adh Migr. 2011 Jan-Feb;5(1):59-64. Epub 2011 Jan 1.

Focal-adhesion targeting links caveolin-1 to a Rac1-degradation pathway. Nethe M, Anthony EC, Fernandez-Borja M, Dee R, Geerts D, Hensbergen PJ, Deelder AM, Schmidt G, Hordijk PL. J Cell Sci. 2010 Jun 1;123(Pt 11):1948-58. doi: 10.1242/jcs.062919. Epub 2010 May 11.

Multi-transcriptional profiling of melanin-concentrating hormone and orexin-containing neurons. Harthoorn LF, Sañé A, Nethe M, Van Heerikhuize JJ. Cell Mol Neurobiol. 2005 Dec;25(8):1209-23.

Retroviral superinfection resistance.  Nethe M, Berkhout B, van der Kuyl AC. Retrovirology. 2005 Aug 18;2:52. Review.