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High affinity anti-idiotype antibody reagents

Contact us via [email protected] to inform about the posibilities to procure any of the antibodies listed below or to generate an anti-idiotype antibody of your interest using our efficient monoclonal antibody pipeline. These antibodies have a proven record of being succesfully implemented as PK assay reagent and as positive control for immunogenicity assessment (see available kits and reagents).

 

Biological

Target

clone

Kd (pM)

Species

Adalimumab

TNF

1.1-1.3; 2.1-2.13

0.7-260

Human

Alemtuzumab

CD52

3E10/3H11

 

Rabbit

Alirocumab

PCSK9

3D1

 

Rabbit

Atezolizumab

PD-L1

1A9

 

Rabbit

Avelumab

PD-L1

1E4

 

Rabbit

Belimumab

BAFF

3B11

 

Rabbit

Brodalumab

IL-17 RA

1D2/5D10/8G8

 

Rabbit

Canakinumab

IL-1ß

2G4/1D5

 

Rabbit

Daratumumab

CD38

4D2

 

Rabbit

Dupilumab

IL-4R

1G11

154

Rabbit

Durvalumab

PD-L1

3D10/1C5

 

Rabbit

Evolocumab

PCSK9

4A7

 

Rabbit

Golimumab

TNF

3H5

 

Rabbit

Guselkumab

IL-23

8C3/4E5

39/204

Rabbit

Infliximab

TNF

1.1-1.4; 2.1-2.4

76-1670

Human

Ixekizumab

IL-17

1C6/2D4

 

Rabbit

Mepolizumab

IL-5

7D12

91

Rabbit

Natalizumab

α4β1/7

1.1/2.1/2.2

10-4700

Human

Nivolumab

PD1

in development

 

Rabbit

Palivizumab

RSV

2E11

10

Rabbit

Pembrolizumab

PD1

1F5

 

Rabbit

Pertuzumab

HER2

in development

 

Rabbit

Reslizumab

IL-5

8H1

86

Rabbit

Secukinumab

IL17

5A9

27

Rabbit

Tocilizumab

IL-6R

7E9

 

Rabbit

Ustekinumab

IL-12/23

4H5

< 5

Rabbit

Vedolizumab

α4β7

1C7

34

Rabbit

Read more about the pipeline in: "Biased anti-idiotype response in rabbits leads to high-affinity monoclonal antibodies to biologics".