Student projects

Student projects

Sanquin offers several interesting and challenging internships for undergraduate students (University master students and HLO trainees). Download the project information below. 

If the internship you are looking for is not there, please have a look at our research groups. If you find something you like, you can contact the reserachers directly.

Open internship projects

 

Laboratory for cell therapy (Carlijn Voermans)

• Uptake analysis of extracellular vesicles using Imaging techniques

 

Phagocyte Laboratory (Timo van den Berg)

• The generation of iPSC to model human disease (Cathelijn Aarts)
   

Hematopoiesis (Emile van den Akker)

• DARC complex arrangements in maturing reticulocytes (Francesca Aglialoro)
• Unraveling the function of band 3 “tyrosine” phosphorylation during erythropoiesis and in erythrocytes
• The contribution of specific cell types to the expansion of erythroblasts from PBMC during the first days of culture
• CRISPR based manipulation of fetal hemoglobin expression in adult cells and generation of an immortal erythroblast cell line

Molecular Cell Biology (Jaap van Buul)

• Physiological flow as a tool to study shear stress-mediated morphological changes in endothelial cells
• Signals that regulate the passage of leukocytes across the vessel wall
• VE-cadherin distribution at cell-cell junctions

 

Plasma Proteins and Research Facilities (Maartje van den Biggelaar)

• Unraveling Factor VIII and FIX activation
• Dissecting endothelial signaling by quantitative mass spectrometry

 

Structure and function of antibodies (Theo Rispens)

• Characterization of IgG dimers/polymers in therapeutic immune globulin preparations
• Antibodies in movement: exchange of antigen binding sites (half-molecules) in IgG4
• The regulation of IgG4 antibody production

 

Trafficking and secretion in the vasculature (Ruben Bierings)

• AP-3 dependent cargo in endothelial Weibel-Palade bodies